I run Pop_OS with a temperamental Nvidia GPU that is unstable at factory clock speeds, but solid when I reduce the power limit by 5-10%. The only recurring annoyance I have with pop is that the flatpak GreenWithEnvy breaks after every GPU driver update and requires a manual flatpak upgrade to fix.
Similarly for my work laptop also running pop on nvidia, the big frustration is again nvidia related. Battery life is poor since hybrid graphics doesn’t work and external displays only work with the discrete graphics card.
If nothing else though, Argo Tuulik’s blog post for Summer Eternal is worth a read. I love his writing style, and that post is unreasonably funny to me, but you can still tell there is a lot of meaning behind what he says. I suppose things hit hardest when presented in ridiculous over the top metaphor.