Blizzard games have always run very well in Wine.

They run, but I wouldn’t say very well. A few counterexamples off the top of my head:

• Wine raw input patches are required to avoid subtle mouse glitches in Overwatch.
• Saving Overwatch highlight videos doesn’t work.
• Battle.net launcher changes have made it unusable in Wine more than once, leaving people suddenly unable to play for days or weeks even when the games themselves would run fine if they could be updated and launched.

You might not notice the problems (or not as often) if using Proton. That’s because Proton includes a load of Wine patches for stuff like this.

It would be nice if Blizzard tested on Wine and worked with the maintainers to ensure things stayed smooth.